The Department of Molecular Biology, Umeå University (Sweden) invites applications for two fully funded PhD positions in Medical Science with an orientation toward Molecular Biology. The projects explore immune system mechanisms and tumor–immune interactions, offering advanced training in a vibrant, multidisciplinary research environment that includes the Laboratory for Molecular Infection Medicine Sweden (MIMS) and the Umeå Centre for Microbial Research (UCMR). Nature Careers
Closing date: 29 Oct 2025
Location: Umeå, Sweden
Employer: Umeå University
Salary: Competitive
Duration: Four-year fixed-term, full-time (start 1 January 2026 or by agreement)
Research Projects
PhD Project 1 – Host Genome Editing and Immune Diversity
Investigate how invertebrate model systems use host genome editing to enhance antigen-receptor diversity. Techniques include CRISPR/Cas9 mutagenesis, imaging, genomics, and single-cell transcriptomics.
PhD Project 2 – Tumor Immune Evasion
Examine how tumor cells escape immune surveillance by hijacking signaling pathways and adhesion molecules. Methods feature high-end microscopy, molecular and biochemical techniques, and lipid-bilayer assays.
Eligibility
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Master’s degree (or equivalent 240 ECTS) with specified coursework:
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≥30 credits chemistry (≥7.5 in biochemistry)
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45 credits biology/molecular biology (≥7.5 genetics, 22.5 microbiology/physiology/cell & molecular biology)
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45 second-cycle credits in cell & molecular biology, including a ≥15-credit independent project
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Proficiency in spoken and written English
Desired Qualifications
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Laboratory experience (essential)
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For Project 1: background in immunology, developmental biology, imaging, microinjection, or CRISPR/Cas9; bioinformatics skills a plus
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For Project 2: background in immunology, cell/molecular biology, imaging, or CRISPR/Cas9; programming for image analysis advantageous
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Strong motivation, independence, teamwork, and communication skills
Selection Criteria
Assessment emphasizes:
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Knowledge and skills relevant to the research area
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Ability to formulate and solve scientific questions
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Written and oral English proficiency
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Research or professional experience, collaborative ability, and initiative
Employment Details
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Goal: Doctoral degree
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Four-year full-time appointment (extension possible if up to 20% teaching is offered)
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Salary according to the university’s PhD salary ladder
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Decision on employment cannot be appealed (Higher Education Ordinance, Ch.12 §2)
Application
Apply online through the Varbi recruitment system by 29 October 2025.
Submit in English or Swedish:
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CV (education, employment, publications)
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Copies of relevant degrees
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Cover letter (research experience, interests, and motivation)
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Contact information for 2–3 referees
For questions, contact ryo.morimoto@umu.se or lena.svensson@umu.se.
Further Information
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Department of Molecular Biology – Department of Molecular Biology
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MIMS – www.mims.umu.se
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UCMR – www.umu.se/en/ucmr
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Research groups: Ryo Morimoto | Lena Svensson
Umeå University is committed to diversity, inclusion, and a positive work environment, welcoming applicants of all backgrounds and identities.