Cancer Genomics, Tumor Evolution, Large-Scale Genomic Data Analysis. Nature Careers
Institution: The University of Texas MD Anderson Cancer Center
Laboratory: Cancer Genomics and Evolution Laboratory
Principal Investigator: Prof. Dr. Peter Van Loo
Department: Department of Genetics
Location: Houston, Texas, USA
Position: Postdoctoral Fellow
Field: Computational Biology / Bioinformatics / Cancer Genomics
Employment: Full-time
Salary: Commensurate with experience
Qualification: PhD
Sector: Academia
Closing Date: 27 October 2026
🔬 Research Focus:
The Cancer Genomics and Evolution Laboratory seeks talented and motivated postdoctoral researchers to spearhead projects in large-scale cancer genomics and tumor evolution. The group uses data-driven computational approaches to investigate cancer genes, mutational processes, genomic alterations and the evolutionary history of tumors.
Research is predominantly computational, with a complementary wet-lab component, and emphasizes large-scale genomic data analysis and development of innovative computational methods.
🌟 Opportunity?
The laboratory has an outstanding publication record, with members having co-authored 22 papers in Nature, Cell or Science. Recent research has addressed:
- Intra-tumor heterogeneity across cancers
- Evolutionary history of cancer
- Biallelic mutations in cancer genomes
- DNA methylation and genomic alterations in lung cancer evolution
- Subclonal reconstruction and benchmarking
- Chromosomal instability in genome-doubled tumors
🎓 Candidate Profile:
Applicants should ideally have:
- A PhD in Computational Biology, Bioinformatics, Genomics or a related field
- A strong and demonstrable publication record
- Research experience in cancer genomics is highly desirable
- Experience handling massively parallel sequencing data is an advantage
- Candidates from computational biology, physics, biostatistics, biology, medicine and related disciplines are welcome
- Strong computational, analytical and problem-solving skills
- Excellent teamwork and collaborative research abilities
🚀 Responsibilities:
Successful postdoctoral researchers will:
- Lead independent projects in cancer genomics and tumor evolution
- Develop and apply computational approaches to large-scale genomic datasets
- Collaborate within the laboratory and with external research partners
- Contribute to multidisciplinary research projects
- Guide and mentor PhD students
- Build an independent research profile in computational cancer biology
📩 How to Apply:
Send the following documents by email:
- Cover letter outlining your career objectives and research interests
- CV, including a complete publication list
- Names/details of three references
Application Email: pvanloo@mdanderson.org
Laboratory Information:
Van Loo Laboratory
Deadline: 27 October 2026
🏛️ Employer: The University of Texas, MD Anderson Cancer Center
An exceptional opportunity for computational biologists and bioinformaticians seeking to work at the forefront of cancer genomics, tumor evolution and large-scale computational biology.