A fully funded PhD position is available in the Nucleic Acid Immunity Lab at VIB–UGent Center for Inflammation Research to investigate the mechanisms of mRNA vaccination and innate immune activation. The successful candidate will join an interdisciplinary research environment focusing on how nucleic acid sensors regulate protective immune responses triggered by mRNA vaccines. Nature Careers
Research Project
Nucleic acids derived from viruses or vaccines can activate intracellular immune sensors, leading to antiviral and protective immune responses. This PhD project aims to identify the nucleic acid sensing pathways responsible for inducing protective immunity following mRNA vaccination.
During the PhD, the candidate will develop expertise in:
- Nucleic acid immunity
- Molecular and cellular biology techniques
- In vivo mouse models of mRNA vaccination
- Advanced immunological research approaches
- The project will be conducted in collaboration with research groups led by
- Sophie Janssens and Stefaan De Smedt to understand the role of nucleic acid sensors in mRNA vaccine responses.
- Candidate Profile
Applicants should have:
- A recently completed or upcoming
- Master’s degree in:
- Biochemistry
- Molecular Biology
- Cell Biology
- Biotechnology
- Biomedical Sciences
- Bioengineering
- Related life science fields
- Willingness to obtain a FELASA C license for animal experimentation
- Strong interest in fundamental biomedical research
- Ability to work independently and collaboratively in an international research team
- Excellent communication skills and fluency in English
What is Offered:
- A doctoral scholarship initially funded for 1 year, renewable for an additional 3 years after successful evaluation
- Support for applying for competitive personal fellowships, including FWO PhD fellowships
- Access to advanced research facilities and training opportunities
- Career development, networking, and mentorship opportunities
- A stimulating and supportive international academic environment
- Expected start date: As soon as possible
- Employment type: Full-time PhD Position
- Research field: Life Sciences / Immunology / Molecular Biology
Location: Ghent, Belgium
Application deadline: 17 August 2026
How to Apply:
Interested candidates should submit:
- Curriculum vitae (CV)
- Motivation letter describing research interests, experience, and motivation
- Contact details of two referees
- Academic transcripts and degree certificates
- Shortlisted candidates will be invited for interviews.
Contact:
Prof. Jonathan Maelfait
VIB–UGent Center for Inflammation Research
Email: jonathan.maelfait@irc.vib-ugent.be
