Recruiter: Aarhus University (AU)
Location: Aarhus, Midtjylland (DK)
Salary: Competitive
Posted: 12 Jul 2023
Closes: 15 Aug 2023
Discipline: Biomedicine, Engineering, Health Science, Life Science
Job Type: PhD Studentship
Employment – Hours: Full time
Duration: Fixed term
Qualification: Masters
Sector: Academia
Applicants are invited for a PhD fellowship/scholarship at Graduate School of Technical Sciences, Aarhus University, Denmark, within the Biological and Chemical Engineering programme. The position is available from 01 November 2023 or later.
Title:
PhD position in Synthetic Biology and Metabolic Engineering
Research area and project description:
Carbon fixation by autotrophs is the major biochemical gateway to the organic world. The utilization of one-carbon compounds such as CO2 and methane (accounting for 76% and 16% of total GHG emission), have been recently drawing attention as a low-cost, abundant feedstock for biochemical production. Transformation of CO2 into (bio)chemicals lies at the center of efforts for sustainable production; and are also key for reducing atmospheric CO2 to mitigate global warming.
It is thus highly desirable to integrate CO2-fixation pathways together with methanol dissimilatory pathway to enable creditable growth of novel genotype of yeast on C1 as sole carbon. This will make it possible to put through a CO2-to-fuel path for an industrial interest.
The objectives of this PhD project are, based on the genotype construction of CO2-fixing autotrophic yeast, 1) Adaptive lab evolution for optimization of recombinant yeast growth on CO2 ; 2) Engineering CO2 fixing yeast strain for drop-in fuels production.
Project description. For technical reasons, you must upload a project description. Please simply copy the project description above, and upload it as a PDF in the application.
Qualifications and specific competences:
Applicants to this PhD position must have a recent, relevant Master’s degree (120 ECTS e.g. metabolic engineering or Biochemical Engineering), with excellent academic record.
Prior experience and knowledge on synthetic biology, metabolic engineering, metabolome analysis, fermentation technique and general molecular biology techniques, and gene editing is desired. Experience with analytical techniques including HPLC, LC-MS/MS, GC-MS and NMR is an advantage.
The ideal candidate has good communication skills, collaborative workstyle; and is also able to work independently.
Place of employment and place of work:
The place of employment is Aarhus University, and the place of work is Gustav Wieds Vej 10A, 8000 Aarhus C
Contacts:
Applicants seeking further information are invited to contact:
Zheng Guo, guo@bce.au.dk or Bekir Engin Eser, bekireser@bce.au.dk
How to apply:
Please follow this link to submit your application. Application deadline is 15 August 2023 23:59 CEST. Preferred starting date is 1 November 2023.
For information about application requirements and mandatory attachments, please see our application guide.
Please note:
The programme committee may request further information or invite the applicant to attend an interview.
Shortlisting will be used, which means that the evaluation committee only will evaluate the most relevant applications.
Aarhus University’s ambition is to be an attractive and inspiring workplace for all and to foster a culture in which each individual has opportunities to thrive, achieve and develop. We view equality and diversity as assets, and we welcome all applicants. All interested candidates are encouraged to apply, regardless of their personal background.
